Crocin, a natural carotenoid pigment isolated from the saffron plant (Crocus sativus), has attracted considerable attention in recent years due to its unique pharmacological properties. Achieving a 99.93% purity level in crocin is of special significance, as pure saffron extract has a wide range of essential pharmaceutical applications, which we will briefly describe here.
Structure and Characteristics of Crocin:
Crocin is a water-soluble compound responsible for the vibrant red color of saffron. Its chemical structure consists of a central dihydroxy β-cyclocitral molecule attached to a disaccharide known as gentiobiose. Understanding the intricacies of crocin's structure is vital for appreciating its purity and bioactivity.
Attaining 99.93% Purity:
The process of obtaining highly pure crocin is a sophisticated and precise endeavor. It involves multiple steps such as saffron extraction, solvent purification, and crystallization, all meticulously performed to
eliminate impurities and contaminants effectively. Achieving this exceptional level of purity ensures the therapeutic efficacy and safety of crocin in pharmaceutical applications.
Our company is dedicated to delivering Crocin of utmost purity, boasting an impressive 99.93% level. Our offerings are accompanied by meticulous certificates and in-depth analytical reports, guaranteeing the highest standards of quality and reliability.Pure Crocin, plays a pivotal role in pharmaceutical applications, ensuring minimal impurities and maximal therapeutic efficacy. We cater to the discerning needs of pharmaceutical professionals, providing a trusted source of this essential compound, fortified by stringent quality control measures and analytical documentation.
Analysis of Pure Crocin
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Technical Data |
Crocin (CAS 42553-65-1) Alternate Names: Bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) 8,8'-diapo-psi, psicarotenedioate; Crocetin gentiobiose ester CAS Number: 42553-65-1 Molecular Weight: 976.96 Molecular Formula: C44H64O24 Physical State : Solid Storage : Store at 4° C Melting Point : 186° C Boiling Point : ~1169.0° C at 760 mmHg (Predicted) Density : ~1.5 g/cm3 |
DEFINITION |
Coloring principle of saffron (dried stigmas of flowers of Crocus sativus L). Crocins are natural drug carotenoid chemical compounds and glycosylated esters of crocetin. |
Physicochemical analysis |
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Physical state |
solid |
Confirmed |
source |
Saffron stigmas |
Confirmed |
solubility |
easily soluble in water and methanol |
Confirmed |
Description |
Deep red color crystals. Orang solution in water |
Confirmed |
Spectrophotometry |
Maximum absorption in water at 440 nm using a 1 cm quartz cell. |
Confirmed |
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Acceptable range |
Result |
Assay (HPLC) |
≥90 |
99.93% |
Loss on drying |
≤ 7.5% |
4% |
Total ash |
≤ 5% |
4.4% |
Microbial analysis |
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Acceptable range |
Result |
Total yeasts and molds count |
≤ 100 cfu/g |
0 cfu/g |
Total aerobic microbial count |
≤ 10000 cfu/g |
0 cfu/g |
Bile-tolerant bacteria gram negative |
≤ 100 cfu/g |
0 cfu/g |
Total coliforms count |
0 cfu/g |
0 cfu/g |
E. coli |
0 cfu/g |
0 cfu/g |
Salmonella species |
0 cfu/g |
0 cfu/g |
Candida albicans |
0 cfu/g |
0 cfu/g |
Pseudomonas aeruginosa |
0 cfu/g |
0 cfu/g |
Staphylococcus aureus |
0 cfu/g |
0 cfu/g |